One can be found inside the hotel, but it is much easier to keep one extra in inventory and bring it along for the quest. A fission battery is required for fixing an access elevator during Reilly's Rangers, at the top of the Statesman Hotel.They are used for powering a wide range of devices like street lamps, electronic signs, light-bulbs, and other household appliances, while being easily scavenged from the common Robot or appliance store, making it invaluable to the common wastelander in the absence of a reliable power grid, if any. Throughout the Mojave Wasteland, fission batteries can be found in New Vegas streets, remote shacks in the wastes, and reoccupied suburban homes.

In post-war society, the fission battery has taken on the role of an on-hand generator. Nuclear energy has the potential to maintain a form for excessive amounts of time. After more than 200 years of inaction, some of the robots can be reactivated, demonstrating that the batteries are a very reliable form of energy storage. As the batteries can often be found in robots, they seem to be their primary energy source, along with powering cars alongside Fusion cores. Even though the exact workings of this item are never undergone, it demonstrates the obsession of the pre-War American society of the Fallout universe with nuclear technologies replacing normal tech, as a means of evolution ( see also: Divergence).

The term 'fission battery' seems to imply that the device's functionality is somehow linked to the process of Nuclear fission, probably some form of alpha//betavoltaic cell or direct charging generator, which is used to generate electrical energy.

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